α / β Arteether is a fast acting blood schuzonticidal agent for Plasmodium falciparum malaria at the erythrocytic stage.
• Severe Malaria including Cerebral Malaria
• And in Second line drug in chloroquine resistant malaria
The functional group responsible for antimalarial activity of a / ß Arteether is endoperoxide bridge. Iron from the digested haemoglobin of the parasite victim reduces this brighe releasing a highly reactive free radical iron species which causes clearance of parasitic cells.
• Nausea
• Dizziness
• Depression
• Gastro-Intenstinal tract activity
BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT THE PATIENT HAS NOW OR HAS HAD. Prolonged QT interval has been reported in some studies with hign dosage of aretemisinin derivatives .The cardiac effects of artemisinin are not very important from clinical point of view ,except that caution should be excercised against combinations with other drugs that prolonged the QT interval, such as quinine and halofantrine.
a / ß Arteether Injection is contraindicated in patients hypersensitive to artemisinin derivatives
From the above discussion, it can be concluded that this a / ß Arteether improve the quality of life from severe malaria and cerebral malaria.
